O-PCE, also known as 2′-Oxo-PCE or Eticyclidone, is a lesser known dissociative agent of the arylcyclohexylamine class. Users report that it is generally more stimulating and causes less cognitive and sensory depression. The experience is described as divided into two parts: the first half with mainly stimulatory heartbeat, loss of motor control, nausea and physical euphoria. Visual effects can include suppression and distortion. Cognitive effects range from memory loss and introspection to slowing down thinking. The substance also has decoupling and transpersonal effects, such as existential self-realization and a sense of unity and interconnectedness. It is important to note that these effects do not occur in a predictable manner and that higher doses may carry a higher risk of negative effects.